Sunday 27 May 2007

In 14 hours.....

I will officially be finished vet school FOREVER!!!!!

I am so excited.....and a little sad. There's some stuff I am really gonna miss.

Lis goes home on tuesday :( I'm really going to miss her nutty presence over the summer.

And now, I should really get back to revising.......histology is gonna bite me in the ass tomorrow.

Oh, Q for all you scientists out there. So, in the neonate, the gut is permeable to whole proteins for a short amount of time to allow absorption of immunoglobulins from colostrum. How does this apply to HIV? Because, as far as I knew, the latest guidelines on breastfeeding in HIV+ mothers, was that exclusively feeding breastmilk in the first 6months gave quite a good chance for the baby to not contract HIV (obv better if getting ONLY formula, but this is where that option is not available). Does anyone know how HIV is not then absorbed? And how are the immunoglobulins not degraded by gastric secretions? I'm afraid I don't know much about this, so any enlightenment would be much appreciated!

1 comment:

Sara said...

Breastfeeding is contraindicated in countries where alternatives are available. It certainly can pass into the infant. The reason not to recommend it in some areas of the world is that the child is more likely to die from diarrheal disease from inappropriately treated water used to mix formula, or from pneumonia from lack of maternal antibody protection, or from just plain malnutrition/starvation for lack of enough good formula, than to contract HIV. HIV does not generally provoke a profound humoral immune response, and there just plain aren't that many protective antibodies against it in any form anyway.

RE: gastric acid in infants - babies don't make a lot of acid at first - which is why they "spit up" and it isn't really like puke. Also, a lot of the protection of secreted antibodies probably comes from effects in the throat and such, rather than in the stomach, before the antibody would be digested.

I am a nerd.